Protein name:
BH3-interacting domain death agonist ;
Alternative:
p22 BID (BID) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein Bcl-2 (By similarity). p15 BID interacts with ITCH.
Function:
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Subcellular Location:
Isoform 2
Mitochondrion membrane
A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.
Protein Attributes:
50:
MDCEVNNGSS | LRDECITNLL | VFGFLQSCSD | NSFRRELDAL | GHELPVLAPQ |
100:
WEGYDELQTD | GNRSSHSRLG | RIEADSESQE | DIIRNIARHL | AQVGDSMDRS |
150:
IPPGLVNGLA | LQLRNTSRSE | EDRNRDLATA | LEQLLQAYPR | DMEKEKTMLV |
195:
LALLLAKKVA | SHTPSLLRDV | FHTTVNFINQ | NLRTYVRSLA | RNGMD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Chicken
Pig
ELISA Kit for Human BH3-interacting domain death agonist
ELISA Kit for Human BH3-interacting domain death agonist
ELISA Kit for Human BH3-interacting domain death agonist
ELISA Kit for Human BH3-interacting domain death agonist
ELISA Kit for Human BH3-interacting domain death agonist
CLIA Kit for Human BH3-interacting domain death agonist
CLIA Kit for Human BH3-interacting domain death agonist
CLIA Kit for Human BH3-interacting domain death agonist
CLIA Kit for Human BH3-interacting domain death agonist
CLIA Kit for Human BH3-interacting domain death agonist
Polyclonal Antibody for Human BH3-interacting domain death agonist
Polyclonal Antibody for Human BH3-interacting domain death agonist
Polyclonal Antibody for Human BH3-interacting domain death agonist
Polyclonal Antibody for Human BH3-interacting domain death agonist
Polyclonal Antibody for Human BH3-interacting domain death agonist
Monoclonal Antibody for Human BH3-interacting domain death agonist
Monoclonal Antibody for Human BH3-interacting domain death agonist
Monoclonal Antibody for Human BH3-interacting domain death agonist
Monoclonal Antibody for Human BH3-interacting domain death agonist
Monoclonal Antibody for Human BH3-interacting domain death agonist
Protein for Human BH3-interacting domain death agonist
Protein for Human BH3-interacting domain death agonist
Protein for Human BH3-interacting domain death agonist
Protein for Human BH3-interacting domain death agonist
Protein for Human BH3-interacting domain death agonist
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.
"A genome annotation-driven approach to cloning the human ORFeome."
Collins J.E.
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Wright C.L.
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Edwards C.A.
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Grinham J.A.
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Cole C.G.
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Genome Biol.5:R84.1-R84.11(2004)
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLY-10
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT GLN-162
tissue :
Brain .
tissue :
Skin .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S.
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Ballif B.A.
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Smogorzewska A.
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McDonald E.R. III
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Hurov K.E.
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Luo J.
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Science316:1160-1166(2007)
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic kidney .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ITCH;UBIQUITINATION BY ITCH
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
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Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
[
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR